Looking for efficiency rather than efficacy in randomized controlled trials in oncology — Ann Oncol
After reading this paper, I am glad that someone had the "balls" to really look at how these trials make a big thing with small results. I remember a chemo regimen, forgot which one, where the length of survival was SIGNIFICANTLY longer than the older regimen, but looking at the data, i was surprised the difference was less than 3 months!!!
Is that how we look at the data, 3 months is significant on paper, but in real life?